Italian scientists have discovered a gene, melanoma

Carrier according to one of the variants of the gene that increases the receptor for vitamin D, the risk of developing melanoma. This is the conclusion on the results of the Italian scientist scoping study. Earlier studies have shown that vitamin D, which is formed in the skin under the influence of sunlight, can play an important role in protecting the body against cancer. This is due to its involvement in the regulation of cell growth, differentiation and apoptosis (programmed cell death). The effects of vitamin D on the human body is arranged on the basis of receptors in the skin. Scientists from the University of Padua suggested that the structure of the receptors for vitamin D influence the activity of the vitamin in the body. Study leader Simone Mosley (Simone Mocellin) and her colleagues at the University of Padua, analyzed the results of six studies involving 4500 patients, half of whom were suffering from melanoma. All participants were carriers of one of the five variants of the gene encoding the receptor for vitamin D. It was found that the carriers of the BsmI gene variant, in which the receptor binds the least amount of vitamin D, the risk of melanoma increased by 30% . Researchers have suggested that this gene variant can Identify each tenth case of melanoma, the. As one of the malignant human tumors The study was published in the journal Cancer.