Basque scientists discovered the opioid and cannabinoid receptors in human sperm and determine its significance for sperm motility by Basque Research. "Newborn" sperm are unable to comprehend the situation, they still have to undergo a process of maturation, which is regulated by a biologically active substances. On the membranes of cell structures are arranged with a specific affinity for these substances - receptors. Researcher Ekayts Agirregoitsiya Marcos (Ekaitz Agirregoitia Marcos) have at the University of the Basque Country found that human sperm, all three known types of opioid receptors (mu, delta and kappa) and both types of cannabinoid (CB1 and CB2), and both in head, and in the tail cells. In the brain, lungs, liver, kidneys, bone marrow and immune cells - Before that opioid receptors were only in the central nervous system, cannabinoid found. Opioid receptors, in addition to their own neurotransmitter molecules drugs, opiates such as heroin and morphine, the cannabinoids - active ingredients of marijuana, such as THC. Agirregoitsiya also shown that sperm motility at least a small part of the delta receptors active. Activation of the mu receptors, but does not inhibit the mobility and kappa receptors. Activation of cannabinoid receptors reduces the translational velocity of the sperm. The study is the basis for new methods of diagnosis and treatment of male infertility.
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