Scientists have six genes erythematosus the risk of disease transmission with systemic lupus

According to scientists for a long time it was thought that the development of systemic lupus erythematosus (SLE) has been influenced by both genetic and environmental factors. Scientists United States, Europe and Scandinavia had to understand 4 studies in an attempt to the causes of the disease and the results published in Nature Genetics and the New England Journal of Medicine. The study identified six genes that increase the risk of SLE 25 to 200 percent. Separately or together, the genes affect the ability of the disease is systemic lupus erythematosus (SLE). Thus, the gene is located on chromosome 16 ITGAM; BLK on chromosome 8; KIAA1542 on chromosome 11, rs10798269 in chromosome 1; PXK on chromosome 3 and BANK1 on chromosome 4 The study involved over 10 thousand people, 13 different genes were examined. The scientists studied the DNA of more than 6,700 people, including those suffering from SLE disease activity, their families and the people without the disease. The study found that most of the increased risk of diagnosed disease in women and mostly in the birth of their children. According to scientists, the new data can be helpful in identifying people who are prone to develop the disease. In addition, based on them are new treatments, by blocking "bad" genes with drugs. The latter is particularly important because the FCC is currently considered incurable. Researchers believe that the next step is to find out the influence of environmental factors such as viruses and pollution on the incidence of SLE.