Saturday, December 15, 2012

Americans have learned, muscular dystrophy treated with stem cells

Models of Duchenne muscular dystrophy - American scientists have full muscle fiber formation is introduced from embryonic stem cells in the muscles of mice. This is the first successful application of stem cells in the treatment of muscular dystrophy. Attempts to treat various forms of hereditary muscular dystrophy with embryonic stem cells were previously made, but every time no results. The fact that immature cells in the theory can be used in muscle following injection into cells of various tissue types transformed turn, form a potentially malignant tumor. To avoid this, preactivated experts Southeastern Medical Center, University of Texas at stem cell gene Pax3, involved in the formation of muscle cells. Thereafter, a part of the cell precursor cells of striated muscle - myoblasts. Researchers could it out from the crowd of other cells with fluorescent substances. Selectively to the cell membrane, which is characteristic for muscle Selected cells thus led to the muscles of the hind legs of rodents. A month later, they spread the muscle tissue, the exchange and the creation of new muscle fibers. The tests were conducted in rodents, the experimental treatment recorded a significant increase in mobility of the hind legs. They have also significantly improved motor coordination. Three months after the injection, the animals were observed for any signs of tumors. In the next stage of the scientists determine whether they want. Myoblasts used safely regeneration of muscle fibers in injuries and injuries during the animal's life Moreover, in the future they will try to use for the treatment of Duchenne muscular dystrophy, an innovative technique of obtaining stem cells from skin cells were successfully tested by American and Japanese scientists.

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