DNA with a similar structure in a position to recognize each other without the help of proteins and other biochemical compounds. These results are the authors of a study published in the Journal of Physical Chemistry. According scientists discovered mechanism allows for the homologous recombination of DNA, which plays an important role in the development of the species. Universal carrier of genetic information, DNA molecule consists of two chains of purine and pyrimidine bases, the coding sequence of amino acids in proteins. Asexual cells of most living organisms (homologous) a double set of DNA molecules consisting of a pair of similar structure. The staff at Imperial College London, the Russian scientist Professor Alexei Kornysheva led studied the behavior of DNA molecules in solution, the other organic compounds deleted. As it turned out, was the DNA and interact with each other, and these interactions have been observed twice as often between homologous molecules. Previously it was thought that the choice of interaction between homologous DNA molecules only possible. With the participation of proteins and other chemical compounds The mechanism of the "telepathic" communication between the DNA is not explained, but scientists suspect that "recognize" these large molecules to each other on the distribution of electrical charges. The probability of such detection increases with the length of the DNA strands. According to the researchers described their interaction used mechanism of homologous recombination - the exchange of genes between similar DNA molecules. This method offers a number of genetic combinations within a species, it is also for the maintenance of the normal structure of the DNA randomly damage important. Understanding the basic mechanism of homologous recombination will allow scientists to better understand the natural defense mechanisms of mutation and improve the methods of genetic engineering and gene therapy.
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