Secret of Moles

Moles on the body, tend to cause positive emotions in others. No wonder that the mole above the lip of supermodel Cindy Crawford arouses admiration of millions of men and women. However, some "fly" can be dangerous, because ultimately become malignant tumor of the skin. Prevent this process will be possible thanks to the recent discoveries of scientists. Melanocytes - melanoma (the scientific name for these tumors) by uncontrolled division of cells synthesize pigment spots formed. , About 30% of melanomas develop at the location of the mole and the same 90% of the moles contained in their cells are cancer causing mutations. How to keep melanocytes from the start of the tumor, has long been a mystery. The answer was found in an unexpected place - the intracellular structure called the endoplasmic reticulum - a kind of guard. Traditionally, the role of the endoplasmic reticulum exclusively in structuring and modification of proteins, which then fall into specific, including health structures. It appeared, however, that it can also detect the position, changes in the level of glucose in the cell, oxygen and other substances, as well as a number of changes that are associated with diseases such as diabetes and Alzheimer's disease. One of the factors stored endoplasmic reticulum melanocytes, the activity of certain oncogenes. In response to the receipt of this signal reticulum triggers the mechanism that prevents cell malignancy. This mechanism leads to cell cycle arrest and prevents cell division, but not murder. These cells are often found in moles, in a "frozen" state for decades, so everyone has a birthmark, but fortunately, melanoma does not occur too often. Identification of the mechanism should be in the identification process, the help specific to the tumor cells and the development of new anticancer drugs.