Conditionally pathogenic bacteria produce a cure for inflammatory bowel disease

Substance that is produced by a type of symbiotic bacteria in the human intestine, can the new medicine for the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease, according to Medical News Today. Researchers at the California Institute of Technology established under the direction of Associate Professor Sarkis Mazmanian (Sarkis K. Mazmanian) that the bacterium Bacteroides fragilis, inhabit the intestine produces a substance called polysaccharide A, which provides for the prevention of inflammation. Can this bacterium belongs to opportunistic pathogens so as a normal part of the intestinal flora, under certain conditions, causing illness. In the experiment, the normal composition of the intestinal flora of mice by introducing disease causing microorganism Helicobacter hepaticus, the disease caused in rodents like ulcerative colitis and Crohn's disease has been disturbed in humans. Mice also entered Bacteroides fragilis, were protected from the disease. The same effect was in animals with the purified polysaccharide A. scientists mechanism such measures explain were treated such that the polysaccharide A stimulated lymphocytes CD4 + (helper T cells), anti-inflammatory protein interleukin-10 (IL-10), also as a factor , inhibits the synthesis of known cytokines (BVK). Thus preventing inflammation of the intestinal wall. According to estimates, affects inflammatory bowel disease, about one million Americans, and the number is growing steadily. Thus, the incidence of Crohn's disease in the U.S. has grown in the last 20 years at 400%.