Monday, May 27, 2013

Acid content of brain cells influence the occurrence of seizures

Increase the acidity of the ion channels of the brain reduces the activity of seizures, say scientists from the University of Iowa. Experts study more than 80 years. Clinical trials in the first half of the 20th Century revealed that the decrease in seizure frequency activity contributes inhalation of carbon dioxide (carbon dioxide), which leads to an increase of the acid in the brain tissue. Seizures reduce the acidity of the nerve tissue. The modern discovery of ion channels responsible for the acidity helped complete the picture of the missing parts. These ion channels are not responsible for the occurrence of seizures, and for the termination of seizure activity, said study author Adam Ziemann. Scientists conducted an experiment in mice, so that the spasms are usually stronger and takes more time in mice that have little of ion channels found (and the gene responsible for their education). Block channels also leads to a prolongation of convulsions and increase the severity of their flow. Stimulation of ion channels provided protection against seizures in mice. Usually the cause of the seizures is is a violation of the synchronous operation of the brain cells. This leads to cramps and spasms. Most seizures stop on their own, but if not, develop life-threatening condition called status epilepticus.

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