Incidence of colon cancer and survival in this disease depends on the sex of the patient, according to U.S. scientists. Researchers have found that the structure of a particular gene that is responsible for the development of colon cancer, has a different predictive value for the different sexes. Initial changes in the structure of the DNA of epidermal growth factor (EGF) have been associated with poor prognosis of colorectal cancer. But when scientists began to look at the EGF receptor as a prognostic factor, it was found that it has a different meaning for men and women. Scientists have the study, which was attended by 318 patients with cancer of the colon. Of these, 177 men and 141 - women who have received special treatment from 1992 to 2003rd All participants underwent chemotherapy. After the analysis of DNA samples, scientists found that women had better survival than men with the same indicators of this factor with high EGF receptor. For the first time, scientists have indicated that the predictive value of the EGF receptor is dependent found sex. Scientists think this is a step to that to secure in the future, and other molecular markers were assessed separately for the different sexes. In appointing therapies have the sex of the patient, not only at the molecular and clinical data, scientists say.
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