Friday, January 4, 2013

Created human embryos with genes from three parents

Employees of the University of Newcastle was the first time a viable human embryos, the cells of the genetic material of the three "parents": use two women and a man scientist's permission, a new technology in medicine: to avoid hybridization eggs that children with a number of serious hereditary diseases. This is a group of disorders associated with mutations in mitochondria - the organelles responsible for energy production. Mitochondria have their own genome, and appear in their genetic disorders will be transmitted to the offspring through the maternal line - along with the mother's egg cell cytoplasm. Mitochondrial dysfunction leads to mental retardation, severe neurological disease, progressive muscular dystrophy, diabetes, blindness and deafness. In the UK there are several hundreds of families at risk children. With such diseases Delete the inheritance of abnormal mitochondria, when I move provided feminonucleus carrier of mitochondrial mutations in donor eggs from a healthy woman. Thus, all of the genetic information contained in the chromosomes, have the child from the mother and father, and his mitochondria are genetically identical to the donor mitochondria women. With such a method, the researchers led by Professor Doug Tornbulla 10 human embryos and brought them to the 5-day stage. Several previously modified in the same way mouse embryos in the uterus of mice had given birth to healthy offspring implanted. Now the scientists. Approval for the implementation of the developed technique in clinical practice If permission is granted, the first of three children of parents in the UK appear in the next three years.

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