Found a new method of chemotherapy previously treatable forms of breast and ovarian cancer

Scientists have found a genetic mechanism that allows for resistant forms of breast and ovarian cancer in people with the defective gene BRCA2 treatment, reports the BBC. The study was published in the journal Nature. There is a tendency to improve the diagnosis and treatment of cancer, however, many tumors develop resistance to the drugs. During the treatment of cancer, unfortunately, a number of side effects, which can cause damage to cellular DNA. Created in a faulty dyudey BRCA2 gene cells initially not in a position to restore the damaged DNA. Can mutate these cells to a malignant tumor. An academic medicine (PARP inhibitors, platinum chemotherapy) were. Most effective in the treatment of tumors with a defective BRCA2 gene in the early stages of the laboratory tests The main part of the test substance is for breast cancer and ovarian cancer conducted. But there is a problem, some of the tumors develop resistance to treatment because of the inability of cells with damaged DNA to recover. However, the last phase of the study showed that some of the cells with damaged DNA can mutate under the influence of the above medications, BRCA2 gene back to normal, so that damage to DNA is prevented and the cells can be returned to normal. Unfortunately it is not possible to neutralize the entire tumor, but it is possible to neutralize the adverse effects of drugs, to DNA damage, which, as Cells can restore their normal structure. The researchers hope that the results will help doctors to take an effective treatment and prevent. The negative effects of drugs