Tuesday, January 8, 2013

Life-age embryos with genes from three parents have not been created

Reports on the establishment of the University of Newcastle researchers viable embryos with genes from three parents were a little premature. In an interview with one of the authors of the Nature study is Chinner Patrick (Patrick Chinnery) reported that hybrid embryos created through the exchange of nuclei between the already fertilized ovum. Scientists used Eggs fertility clinics were rejected because of the chromosomal mutations. Therefore resulting embryos will not be viable, said Chinner. Moreover, not all experiments by transfer of nuclei were successful. "We still remain a number of unresolved questions. It's about as effective process (nuclear transfer) and the possibility of she spends with eggs, not just with zygotes" - So the scientists. Previously, the British press reported that researchers from the University of Newcastle to viable embryos managed to get through nuclear transfer fertilized egg (zygote) to the mature, but not fertilized egg. So, allegedly received more full of human embryos in the laboratory brought before the fifth day of development. Newcastle University has a license to consult experiments with embryos from three parents in 2005. Theoretically, this technique can avoid the birth of children to help with genetic defects in the mitochondria - cellular organelles responsible for energy production. Mitochondria have their own DNA, which encodes about one thousandth of the total genetic information in the cell. Unlike nuclear DNA, mitochondrial DNA only performed on the offspring by the mother, with the cytoplasm of the egg. Hereditary mitochondrial dysfunction causes several serious diseases that lead to defects in the internal organs, muscular dystrophy and mental retardation. To avoid the inheritance of mitochondrial mutations, the researchers suggest the female fertilized egg core carriers of mutations in the egg transfer, which is a healthy female donor. Developed from an egg fruit a mother and father have the genes, but the mitochondria are genetically identical to a full donor mitochondria.

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