Developed an effective method of obtaining stem cells from skin

American company PrimeGen indicated that they in a position to safe way to transform cells in tissue, similar could develop the characteristics of pluripotent stem cells. The resulting new method, cells are viral vectors - it reduces the likelihood of degeneration in malignant tumors. Induced pluripotent stem cells (iPS cells), cells from the skin and other tissues of the adult body, which is derived as one of the most promising areas of cellular technologies. Like embryonic stem cells, they can be transformed into cells of all tissue types, but their teachings must not destroy human embryos. Moreover, these cells from the patient's own cells, in which case they would be genetically identical to obtain the tissue of the patient and not be rejected by the immune system of the graft. First useful lines of human iPS cells are created in the past year by two independent groups of scientists from Japan and the USA. In both cases, the transformation of cells using retroviruses carrying extra copies of genes that regulate cell differentiation processes. Resulting cell lines were infected with viral vectors, which greatly increased the likelihood of their rebirth in potentially malignant cells. Moreover embedded additional copies of genes in the genome, and. To subsequent generations of stem cells, which could also lead to unwanted adverse effects PrimeGen experts managed to circumvent these problems by replacing the retrovirus carbon particles, to which were attached a copy of the necessary genes. Once inside the cell, the particles are applied as genes, but the genes of them are not performed, and integrated into the genome. To subsequent generations of cells The company was able to obtain the induced pluripotent stem cells from skin cells, kidney and retina. Another advantage of the new method, according to developers, is the high productivity. For example, Japanese scientists took about a month to get a colony of stem cells skin cells. PrimeGen technique reduces the conversion of cells to a week and the number of cell lines to several hundred times to increase.